Why ask God to bless work I am already doing myself?
Look at the order in the Torah. The builders of the Mishkan did everything first: "as Hashem commanded, so they did." Only then: "Moshe blessed them." The blessing did not replace the work. It came after it.
The prayer repeats "the work of our hands," and Rashi, on Tehillim 90:17, says the repeat has two meanings. One is the work of the Mishkan itself, that God's Presence rest on what they built. The other is wider: a blessing on the work of their hands in general.
What does "establish" mean? Ibn Ezra says: set the causes and circumstances right, so that they have no burden and toil in all they do, and then make the work whole, as in the verse that begins "Unless Hashem builds the house" (Tehillim 127:1). Metzudat David (a line-by-line commentary on Tehillim, from the 1700s) says: let nothing go wrong while we are doing the work.
That is also why the rule for when to say it is so practical. The Tur and the Mishnah Berurah say it is skipped when a Yom Tov falls in the coming week. It is a prayer for work, so it needs a week with work in it.
The sources do not say where your effort ends and God's help begins. They put both in the same picture: builders who built, and a blessing for their hands.
Shemot 39:43,Rashi, Ibn Ezra and Metzudat David on Tehillim 90:17,Tur, Orach Chaim 295; Mishnah Berurah 295:3I do not believe in demons. Is this psalm about them?
Some of the oldest sources say yes. The Gemara calls this psalm a song against pega'im, and Rashi explains the word as harmful beings that strike people (Shevuot 15b).
Elsewhere (Berakhot 6a) the Gemara says that if the eye were allowed to see the mazikim, the harmful beings, no creature could stand it. Rav Huna, a Gemara teacher in Babylon, adds that each of us has a thousand of them at his left and ten thousand at his right, which echoes the psalm's "a thousand will fall at your side, ten thousand at your right." Rava blames them for the crowding at big Torah gatherings, for tired knees, and for scholars' clothes that wear out.
Rashi follows this reading. On the psalm's plague "in darkness" and plague "at noon," he says the two Hebrew words are names of such beings, one that harms at night and one at noon. He sends us to Pesachim 111b, where the Gemara says "ketev yashud tzaharayim" is the name of one of them.
Other commentators read the same verses without them. Ibn Ezra explains by weather: most plague strikes at night when the cause is cold, and at midday when the cause is heat. (He also notes that some connect one of the words to shedim, demons.) Radak says the "arrows" are the sudden events of life, and night is frightening because a person alone in the dark is afraid. The thousand who fall could be soldiers in a war, he says, or victims of an epidemic.
So two old readings sit side by side: invisible forces, or the ordinary dangers of life. The psalm does not pick one for you. What Rashi and Radak share is a condition, "if you trust Him," which the next question looks at.
Shevuot 15b with Rashi; Berakhot 6a,Rashi on Tehillim 91:6; Pesachim 111b,Ibn Ezra on Tehillim 91:6,Radak on Tehillim 91:5 and 91:7Does this psalm promise that nothing bad will happen to me?
"No evil will befall you, and no plague will come near your tent." That sounds like a guarantee. Good people do get hurt, so a fair reader asks what it really claims.
The commentators do not read it as unconditional. On "you will not fear," Rashi writes "if you trust Him." Radak, explaining the opening verses, adds the same words. Ibn Ezra hears a person speaking, not a contract: he reads the opening as someone saying, "I tried this myself, and I will vouch for it."
The Gemara adds a limit from the other side. Rabbi Yannai, a Gemara teacher, said a person should never stand in a dangerous place and say a miracle will be done for him, because maybe it will not, and if it is, it is taken from his merits (Shabbat 32a).
The Midrash on Tehillim reads "your tent" as the Mishkan. Rabbi Yochanan (a Gemara teacher in the Land of Israel) says that before the Mishkan stood, harmful forces troubled people, and once it stood, "no plague will come near your tent" came true. Another teacher, Reish Lakish, finds the same in the Priestly Blessing, "May Hashem bless you and guard you," which the Midrash dates to the day the Mishkan was set up.
So the commentators do read a real promise here, but one made to a person who trusts God and makes Him his shelter. Radak says so on verse 9: all this peace will be yours because you made the Most High your dwelling. The Gemara adds that you still have to watch your step. The Midrash ties the protection to a place where God's Presence was. None of these sources explains why good people who trust God still get hurt. That question stays open, and the text leaves it with you.
Rashi on Tehillim 91:5; Radak on Tehillim 91:1 and 91:9; Ibn Ezra on Tehillim 91:2,Shabbat 32a,Midrash Tehillim 91:4